| Anmol Chemicals is the pioneer manufacturers of Sodium Sulfate Anhydrous Decahydrate and Sodium Thiosulfate Anhydrous Pentahydrate, Pharmaceutical Excipients Fragrance Food & Flavor chemicals in India. We supply Halal and Kosher Sodium Sulfate and Sodium Thiosulfate Anhydrous Pentahydrate made in an ISO9001, ISO22000 (FSSC22000) cGMP and GLP certified facility. Our group has several manufacturing facilities spread across the world, supported by toll manufacturers and representatives in UAE, Europe, USA, China and has several associated manufacturing facilities spread across India. All the Information on Physics, Chemistry, Applications, Uses and Technology on Manufacture of Sodium Sulfate and Sodium Thiosulfate Anhydrous Pentahydrate is in these pages. |
| The units have one or more of the certifications like FDA GMP, ISO 9001, ISO 22000, HACCP, REACH, Kosher & Halal |
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Sodium Sulfate Anhydrous Decahydrate and Sodium Thiosulfate Anhydrous Pentahydrate EP BP Ph Eur USP NF IP FCC Food Grade Manufacturers
Sodium Sulfate Anhydrous CAS Number 7757-82-6 & Sodium Sulfate Decahydrate CAS Number 7727-73-3
Sodium Thiosulfate Anhydrous CAS Number 7772-98-7 & Sodium Thiosulfate Pentahydrate CAS Number 10102-17-7
Anhydrous Sodium Sulphate BP Ph Eur EP Grade Specifications
Na2SO4
Action and use: Laxative.
DEFINITION
Content: 98.5 per cent to 101.0 per cent (dried substance).
CHARACTERS
Appearance: White or almost white powder, hygroscopic.
Solubility: Freely soluble in water.
IDENTIFICATION
A. It gives the reactions of sulphates.
B. It gives the reactions of sodium.
C. It complies with the test for loss on drying (see Tests).
TESTS
Solution S: Dissolve 2.2 g Sodium Sulfate in carbon dioxide-free water R prepared from distilled water and dilute to 100 ml with the same solvent.
Appearance of solution: Solution S is clear and colourless.
Acidity or alkalinity: To 10 ml of solution S add 0.1 ml of bromothymol blue solution R1. Not more than 0.5 ml of 0.01 M hydrochloric acid or 0.01 M sodium hydroxide is required to change the colour of the indicator.
Chlorides: Maximum 450 ppm.
Calcium: Maximum 450 ppm, if intended for use in the manufacture of parenteral dosage forms.
Iron: Maximum 90 ppm, if intended for use in the manufacture of parenteral dosage forms.
Magnesium: Maximum 200 ppm, if intended for use in the manufacture of parenteral dosage forms. To 10 ml of solution S add 1 ml of glycerol (85 per cent), 0.15 ml of titan yellow solution, 0.25 ml of ammonium oxalate solution and 5 ml of dilute sodium hydroxide solution and shake. Any pink colour in the test solution is not more intense than that in a standard prepared at the same time in the same manner using a mixture of 5 ml of magnesium standard solution (10 ppm Mg) and 5 ml of water.
Heavy metals: Maximum 45 ppm.
Loss on drying: Maximum 0.5 per cent, determined on 1.000 g by drying in an oven at 130C.
Sodium Sulfate USP Grade Specifications
Na2SO4-10H2O - 322.20
Sulfuric acid disodium salt, decahydrate.
Disodium sulfate decahydrate [CAS Number 7727-73-3]
Anhydrous 142.04 [CAS Number 7757-82-6]
Sodium Sulfate contains ten molecules of water of hydration, or is anhydrous. It contains not less than 99.0 percent of Na2SO4, calculated on the dried basis.
Identification: A solution (1 in 20) responds to the tests for Sodium 191 and for Sulfate.
Acidity or alkalinity: To 10 mL of a solution, containing the equivalent of 1.0 g of Na2SO4·10H2O in 20 mL of water, add 1 drop of bromothymol blue TS: not more than 0.50 mL of either 0.010 N hydrochloric acid or 0.010 N sodium hydroxide is required to change the color of the solution.
Loss on drying: Dry at 105 for 4 hours: the decahydrate loses between 51.0% and 57.0% of its weight, and the anhydrous form loses not more than 0.5% of its weight.
Chloride: A portion equivalent to 1.0 g of Na2SO4·10H2O ( Sodium Sulfate Decahydrate )shows no more chloride than corresponds to 0.30 mL of 0.020 N hydrochloric acid (0.02%).
Sodium Sulphate EP Ph Eur Grade Specifications:
Characters: It occurs as a white or almost white powder, hygroscopic.
Identification:
(a)It gives the reactions of sulphates.
(b)It gives the reactions of sodium.
(c)It complies with the test for Loss on drying.
Solubility: Freely soluble in water.
Appearance of solution: Solution S is clear and colorless
Acidity or alkalinity: To 10ml of solution S add 0.1ml of bromothymol blue solution R1. Not more than 0.5ml of 0.01 M hydrochloric acid or 0.01 M sodium hydroxide is required to change the color of the indicator.
Chlorides: Maximum 450 ppm
Calcium: Maximum 450 ppm
Iron: Maximum 90 ppm
Magnesium: Maximum 200 ppm
Heavy metals: Maximum 45 ppm
Loss on drying:Maximum 0.5%
Assay: Not less than 98.5% and not more than 101.0% (dried substances).
Sodium Sulfate FCC Food Grade Specifications
Na2SO4-10H2O .. 322.20
Sulfuric acid disodium salt, decahydrate.
Disodium sulfate decahydrate [CAS Number 7727-73-3].
Anhydrous 142.04 [CAS Number 7757-82-6].
Sodium Sulfate contains ten molecules of water of hydration, or is anhydrous. It contains not less than 99.0 percent of Na2SO4, calculated on the dried basis.
Packaging and storage: Preserve in tight containers, preferably at a temperature not exceeding 30C.
Identification: A solution (1 in 20) responds to the tests for Sodium and for Sulfate.
Acidity or alkalinity: To 10 mL of a solution, containing the equivalent of 1.0 g of Na2SO4·10H2O in 20 mL of water, add 1 drop of bromothymol blue TS: not more than 0.50 mL of either 0.010 N hydrochloric acid or 0.010 N sodium hydroxide is required to change the color of the solution.
Loss on drying: Dry at 105 for 4 hours: the decahydrate loses between 51.0% and 57.0% of its weight, and the anhydrous form loses not more than 0.5% of its weight.
Chloride: A portion equivalent to 1.0 g of Na2SO4·10H2O shows no more chloride than corresponds to 0.30 mL of 0.020 N hydrochloric acid (0.02%).
Heavy metals: the limit is 0.001%.
Sodium Sulfate Anhydrous Analytical Reagent Specifications
Na2SO4
Formula Wt 142.04
CAS Number 7757-82-6
REQUIREMENTS
Assay: 99.0% Na2SO4
pH of a 5% solution: 5.2-9.2 at 25C
MAXIMUM ALLOWABLE
Insoluble matter: 0.01%
Loss on ignition: 0.5%
Chloride (Cl): 0.001%
Nitrogen compounds (as N): 5 ppm
Phosphate (PO4): 0.001%
Heavy metals (as Pb): 5 ppm
Iron (Fe): 0.001%
Calcium (Ca): 0.01%
Magnesium (Mg): 0.005%
Potassium (K): 0.01%
Sodium Sulfate, Decahydrate Analytical Reagent Specifications
Na2SO4-10H2O
Formula Wt 322.19
CAS Number 7727-73-3
REQUIREMENTS
Assay: 99.0% Na2SO4-10H2O
pH of a 5% solution: 5.2-9.2 at 25C
MAXIMUM ALLOWABLE
Insoluble matter: 0.01%
Chloride (Cl): 5 ppm
Nitrogen compounds (as N): 3 ppm
Phosphate (PO4): 5 ppm
Heavy metals (as Pb): 3 ppm
Iron (Fe): 5 ppm
Calcium (Ca): 0.005%
Magnesium (Mg): 0.003%
Potassium (K): 0.005%.
Specifications of Sodium Thiosulfate Anhydrous surpassing all the standards:
Description: It appears as white powder free from foreign particles.
Solubility 10% aqueous solution: Freely soluble in water.
Identification
(A)Reaction of Sodium
(B)Reaction of Thiosulphate: A solution responds to the test for Sodium and for Thiosulphate
Insoluble Matter: Not more than 0.25%
Calcium: Prescribed Test. No turbidity is produced.
pH: 6 to 8.4
Sulphites and Sulphates: Maximum 0.5%
Heavy Metals: Maximum 0.001%
Sodium Sulphite: Maximum 0.2%
Iron as Fe: Not more than 0.001%
Residual Solvent: To meet the requirement
Assay: Not less than 99% and not more than 100.5% of Na2S2O3 on anhydrous basis.
Sodium Thiosulfate USP Grade Specifications
Na2S2O3-5H2O - 248.19
Sodium Thiosulfate USP
Contains not less than 99.0 percent and not more than 100.5 percent of Na2S2O3, calculated on the anhydrous basis.
Packaging and storage: Preserve in tight containers.
Identification:
A: To a solution (1 in 10) add a few drops of iodine TS: the color is discharged.
B: A solution (1 in 10) responds to the tests for Sodium and for Thiosulfate.
Water: Dry about 1.0 g, accurately weighed, in vacuum at 40 o to 45o for 16 hours: it loses between 32.0% and 37.0% of its weight.
Calcium: Dissolve 1 g Sodium Thiosulfate in 20 mL of water, and add a few mL of ammonium oxalate: no turbidity is produced.
Heavy metals: the limit is 0.002%.
Sodium Thiosulphate BP Ph Eur Grade Specifications
Na2S2O3-5H2O
Sodium Thiosulphate BP
DEFINITION
Content: 99.0 per cent to 101.0 per cent of Na2S2O3,5H2O.
CHARACTERS
Appearance: Transparent, colorless crystals, efflorescent in dry air.
Solubility: Very soluble in water, practically insoluble in ethanol 96 per cent. It dissolves in its water of crystallization at about 49C.
IDENTIFICATION
A. It decolorizes iodinated potassium iodide solution.
B. To 0.5 ml of solution S (see Tests) add 0.5 ml of water R and 2 ml of silver nitrate solution. A white precipitate is formed which rapidly becomes yellowish and then black.
C. To 2.5 ml of solution S add 2.5 ml of water and 1 ml of hydrochloric acid. A precipitate of sulphur is formed and gas is evolved which gives a blue colour to starch iodate paper.
D. 1 ml of solution S gives reaction of sodium.
TESTS
Solution S: Dissolve 10.0 g in carbon dioxide-free water R prepared from distilled water R and dilute to 100 ml with the same solvent.
Appearance of solution: The freshly prepared solution is clear and colourless.
Dissolve 10.0 g in 50 ml of distilled water, add 1 ml of 0.1 M sodium hydroxide and dilute to 100 ml with the same solvent.
pH: 6.0 to 8.4 for the freshly prepared solution S.
Sulphates and sulphites: Maximum 0.2 per cent.
Sulphides: To 10 ml of solution S add 0.05 ml of a freshly prepared 50 g/l solution of sodium nitroprusside. The solution does not become violet.
Heavy metals: Maximum 10 ppm.
Specifications of Sodium Thiosulfate FCC Food Grade
Sodium Hyposulfite
Na2S2O3-5H2O Formula weight 248.19
DESCRIPTION
Sodium Thiosulfate or Sodium Thiosulphate occurs as large, colorless crystals or as a coarse, crystalline powder. It is deliquescent in moist air and effloresces in dry air at a temperature above 33C. Its solutions are neutral or faintly alkaline to litmus. One gram dissolves in 0.5 mL of water. It is insoluble in alcohol.
Function: Sequestrant; antioxidant.
REQUIREMENTS
Identification
A. Add a few drops of iodine TS to a 1:10 aqueous solution. The color disappears.
B. A 1:20 aqueous solution gives positive tests for Sodium and for Thiosulfate.
Assay: Not less than 99.0% and not more than 100.5% of Na2S2O3 after drying.
Lead: Not more than 2 mg/kg.
Selenium: Not more than 0.003%.
Water: Between 32.0% and 37.0%.
Specifications of Sodium Thiosulfate Pentahydrate or Sodium Thiosulphate Analytical Reagent
Na2S2O3-5H2O
Formula Weight 248.19
CAS Number 10102-17-7
REQUIREMENTS
Assay: 99.5-101.0% Na2S2O3-5H2O
pH of a 5% solution: 6.0-8.4 at 25C
MAXIMUM ALLOWABLE
Insoluble matter: 0.005%
Nitrogen compounds (as N): 0.002%
Sulfate and sulfite (as SO4): 0.1%
Sulfide (S): Passes test
Sodium Sulfate Anhydrous Decahydrate and Sodium Thiosulfate Anhydrous Pentahydrate Manufacturers
Anmol Chemicals
S-8, SARIFA MANSION, 2ND FLANK ROAD, CHINCHBUNDER, MUMBAI 400009, INDIA
TEL: (OFFICE) 91-22-23770100, 23726950, 23774610, 23723564. FAX: 91-22-23728264
e-mail: anmolc@mtnl.net.in
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